Nagini was Voldemort's snake and one of his 7 horcruxes. In Harry Potter and the Deathly Hallows, Neville killed Nagini with the Sword of Gryffindor during the battle of Hogwarts.  Some people think that the boa constrictor Harry set on Dudly at the zoo is Nagini, but this is a rumor as Nagini is truly an undefined snake  

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